The cast ofLittlemouth, a sci-fi mystery, has been announced.Isabelle FuhrmanandDennis Quaidwill play the leading roles, joined by David Thewlis, Josh Hutcherson, and Kiera Allen. Jonathan Sobol both wrote and directed the movie. Nicholas Tabarrok is producing alongside William G. Santor and Doug Murray, the latter of whom work for Productivity Media. Mimi Steinbauer’s Radiant Films will handle the international distributing rights.

Fuhrman has most recently appeared in the Shudder original filmThe Last Thing Mary Saw. Her breakout role was in the psychological horror filmOrphan, which she’ll reprise in the upcoming prequelOrphan: First Kill.Littlemouthwill be the first time she’ll work alongside Hutcherson since the firstHunger Gamesmovie.

Isabelle Fuhrman as Esther in “Orphan”

Quaid’s recent film credits includeAmerican Underdog, Midway,andA Dog’s Journey, alongside such series as Prime’sGoliathand Netflix’sMerry Happy Whatever. Among other things, he’ll also soon appear inJeff Celentano’s baseball dramaThe Hill, Disney animated film Stange World, and two Sam McNamara dramas, which areReaganandOn a Wing and a Prayer.

Thewlis has made appearances in both theHarry PotterandDC Extended Universefranchises. Besides that, he also appeared in season 3 of the FX anthology showFargoand on the Netflix Original animated seriesBig Mouth. Some of his upcoming films will beEnola Holmes 2andAvatar 3.

Hutcherson is best known for appearing in all fourHunger Gamesfilms. He’s also been in such movies asThe Disaster Artist, Journey to the Center of the Earth, Kicking & Screaming, andThe Kids Are All Right. In the lead role, Hutcherson also recently starred in the Hulu seriesFuture Man. An upcoming film of his is the sci-fi thriller57 Secondswith Morgan Freeman.

Allen is best known for starring in the Hulu thrillerRunalongside Sarah Paulson, which was also her feature film debut. According to IMDb, she became the first real-life wheelchair user to star in a major thriller in 73 years, since Susan Peters inThe Sign of the Ram. Allen has also appeared on an episode ofThe Good Doctor.

Related:Dennis Quaid’s New Bonniedale Productions Sets Charley Pride Biopic as First Feature

Littlemouth is a Story Jonathan Sobol is Passionate About

“This is a story I am passionate about telling and I’m thrilled and humbled with the cast that has come together to bring it to life. With Isabelle Fuhrman in the lead, working with an icon like Dennis Quaid and the incomparable David Thewlis (one of my all-time favorite actors), to younger stars like Josh and Keira – I simply couldn’t have asked for a better group of artists to work with,” said Sobol during an interview, courtesy ofDeadline.

The film’s plot will follow a brilliant computer scientist (Fuhrman) who is recruited by a charismatic tech billionaire (Quaid) to work on a secret project that might, in fact, change humanity’s place in the universe. Of course, the opportunity comes at great risk. It is currently not known who Thewlis, Hutcherson, and Allen will play.

“When I read Jonathan’s original screenplay, I was so taken by the creative spin that he had taken on the sci-fi genre. His script makes the reader think about decisions made by scientists and how they affect the world around us and beyond. He is the only filmmaker that could direct his script into a film that genre fans will love,” said Santor.